Gene Editing

Precision RNA Tools for Genome Engineering

High-fidelity RNA for gene editing applications
Gene editing technologies rely on RNA as a precise and transient effector for genome modification. High-quality sgRNA design, synthesis, and delivery are critical for achieving accuracy, efficiency, and reproducibility in gene editing workflows.

Crystal NAX supports gene editing programs through high-fidelity sgRNA synthesis, advanced RNA delivery systems, and robust analytical characterization. Our technologies enable precise evaluation and optimization of RNA-based genome engineering tools in research and preclinical settings.

Key Capabilities

gene editing scheme
  • mRNA and self-amplifying RNA design and optimization
  • Sequence engineering for expression, stability, and developability
  • Flexible synthesis workflows supporting rapid iteration
  • Enzymatic sgRNA synthesis with high sequence accuracy
  • Support for long and complex guide RNA constructs
  • Reproducible workflows for CRISPR-based applications
  • LNP formulation optimized for gene editing payloads
  • Flexible delivery design tailored to target cells and tissues
  • Integration with high-throughput screening platforms
  • Analytical evaluation of RNA integrity and quality
  • Functional assessment of editing efficiency and consistency
  • Data-driven optimization of gene editing systems

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