Animal Immunization

mRNA-Enabled Animal Immunization

Accelerating antibody and protein discovery through in vivo mRNA expression

mRNA–LNP immunization enables direct in vivo expression of target antigens or proteins, offering a powerful alternative to traditional protein- or antibody-based immunization strategies. By delivering mRNA instead of purified proteins, antigens are produced in their native or near-native conformations within the animal, often resulting in improved immunogenicity and broader epitope coverage.

Crystal NAX supports animal immunization workflows tailored for antibody generation and protein discovery providers. Our integrated RNA design, LNP delivery, and analytical platforms enable faster timelines, reduced protein engineering burden, and greater flexibility in antigen design and optimization.

Optimization of RNA systems designed for precise cellular modulation in preclinical research.

Why mRNA–LNP for Animal Immunization

Eliminates the need for complex protein expression, purification, and formulation
Enables in vivo expression of difficult, unstable, or membrane-associated antigens
Supports rapid iteration of antigen sequences and formats
Often improves immune response quality by presenting antigens in native conformations
Shortens immunization cycles and accelerates antibody discovery programs