How to Choose the Best Cas9 mRNA for Gene Editing
The best Cas9 mRNA for gene editing is defined by transcript integrity, dsRNA content, capping efficiency, nucleotide modification strategy, and functional validation in a cell-based potency assay. This guide explains what how to evaluate batch data, for researchers working proof of concept to early IND-enabling studies.
How Double-Stranded RNA (dsRNA) Jeopardize RNA Therapeutics
Double-stranded RNA (dsRNA) is an intrinsic IVT impurity that activates immune responses, suppresses translation, and must be controlled within CMC strategy for RNA therapeutics.
RNA Therapeutics Explained: RNA Types, Delivery and Manufacturing
RNA therapeutics include multiple RNA types with distinct mechanisms, but delivery systems and manufacturing determine whether an RNA concept becomes a reproducible, safe medicine.
Lipid Nanoparticles for mRNA Therapies Delivery
Lipid nanoparticles enable RNA delivery through controlled uptake and limited endosomal escape. Experimental outcomes depend on formulation and biology.
Join our San Diego Biotech Networking Event: RNA and LNP
Join Crystal NAX in this San Diego biotech networking event focused on RNA CMC, LNP delivery, and development strategy.
CPHI Frankfurt 2025: Crystal NAX Showcase with the Crystal Pharmatech Group
Discover the advancements presented at CPHI Frankfurt 2025, where Crystal NAX showcased with the Crystal Pharmatech family. This event highlighted our innovative capabilities in nucleic acid therapeutics, including RNA design, synthesis, and delivery technologies.
Join our San Diego Biotech Networking Event: RNA and LNP
Join Crystal NAX in this San Diego biotech networking event focused on RNA CMC, LNP delivery, and development strategy.
CPHI Frankfurt 2025: Crystal NAX Showcase with the Crystal Pharmatech Group
Discover the advancements presented at CPHI Frankfurt 2025, where Crystal NAX showcased with the Crystal Pharmatech family. This event highlighted our innovative capabilities in nucleic acid therapeutics, including RNA design, synthesis, and delivery technologies.
How to Choose the Best Cas9 mRNA for Gene Editing
The best Cas9 mRNA for gene editing is defined by transcript integrity, dsRNA content, capping efficiency, nucleotide modification strategy, and functional validation in a cell-based potency assay. This guide explains what how to evaluate batch data, for researchers working proof of concept to early IND-enabling studies.
How Double-Stranded RNA (dsRNA) Jeopardize RNA Therapeutics
Double-stranded RNA (dsRNA) is an intrinsic IVT impurity that activates immune responses, suppresses translation, and must be controlled within CMC strategy for RNA therapeutics.
RNA Therapeutics Explained: RNA Types, Delivery and Manufacturing
RNA therapeutics include multiple RNA types with distinct mechanisms, but delivery systems and manufacturing determine whether an RNA concept becomes a reproducible, safe medicine.
Lipid Nanoparticles for mRNA Therapies Delivery
Lipid nanoparticles enable RNA delivery through controlled uptake and limited endosomal escape. Experimental outcomes depend on formulation and biology.